Experimental Treatment Options in Absence Epilepsy

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Experimental Models of Absence Epilepsy; A Review Article

Background: Absence epilepsy is a brief non-convulsive seizure that associated with sudden abrupt in consciousness. Because of the unpredictable occurrence of absence seizures and ethic limitation of human investigation on the pathogenesis and drug assessment led to the tendency to animal models. The aim of this paper is reviewing the advantages and disadvantages of several animal models of non...

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The modern antiepileptic drug (AED) era--spanning a period of more than 150 years from the first use of bromide in 1857 to 2008--has seen the introduction into clinical practice of a diverse group of effective and safe drugs. These AEDs have provided considerable benefits for those afflicted with epilepsy of all kinds. In as many as 60-70% of newly treated patients, current AEDs lead to satisfa...

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Traumatic brain injury (TBI) leads to many undesired problems and complications, including immediate and long-term seizures/epilepsy, changes in mood, behavioral, and personality problems, cognitive and motor deficits, movement disorders, and sleep problems. Clinicians involved in the treatment of patients with acute TBI need to be aware of a number of issues, including the incidence and preval...

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ژورنال

عنوان ژورنال: Current Pharmaceutical Design

سال: 2018

ISSN: 1381-6128

DOI: 10.2174/1381612823666171017170226